Ashwagandha
KSM-66 Ashwagandha
Last reviewed: June 2026 · Medically reviewed by a licensed pharmacist
What it does
Ashwagandha is an adaptogen, a plant that helps the body cope with stress. Clinical trials show standardized root extracts can lower cortisol (your main stress hormone) and reduce feelings of stress and anxiety, typically over about eight weeks. It's one of the better-studied calming botanicals, valued for taking the edge off without sedation.
The science
KSM-66 ashwagandha reduces cortisol by 20-30% in clinical trials, improves stress resilience, sleep quality, and testosterone in men under chronic stress.
Most relevant for
Ongoing stress, feeling wired, and stress-related poor sleep.
Key references
General wellness information, not medical advice. Consult your healthcare provider before starting any supplement. Build your personalized stack →