Berberine

What it does

Berberine is a plant compound that's become popular for supporting healthy blood sugar and metabolism. Clinical trials suggest it can help the body manage glucose and improve metabolic markers, which is why it's sometimes called nature's metabolic helper. It's potent and can interact with medications, so it's one to clear with your doctor first.

The science

Berberine activates AMPK, the metabolic master switch, improving insulin sensitivity, blood glucose, and lipid metabolism comparably to metformin in some studies.

Most relevant for

Metabolic and blood-sugar support. Check with your doctor if you take any medication.

Key references

• Examine.com: Berberine — research summary
• MyStaq Clinical Elements Library