Folate

L-Methylfolate

Last reviewed: June 2026 · Medically reviewed by a licensed pharmacist

What it does

Folate is essential any time your body builds new cells, which is constant, but especially critical before and during pregnancy for a baby's healthy development. It also helps keep homocysteine (a marker tied to heart health) in check. We use the active L-methylfolate form, which the body can use directly without an extra conversion step that some people struggle with.

The science

Folate (as methylfolate) is essential for DNA synthesis, cell division, and homocysteine metabolism. Critical during pregnancy for neural tube development.

Most relevant for

Anyone trying to conceive or pregnant, and people with the MTHFR gene variant.

Key references

General wellness information, not medical advice. Consult your healthcare provider before starting any supplement. Build your personalized stack →