Vitamin B6

Pyridoxine

Last reviewed: June 2026 · Medically reviewed by a licensed pharmacist

What it does

B6 is a key helper in making the brain's messenger chemicals: serotonin, dopamine, GABA, which influence mood, sleep, and focus. It's also needed to use protein and to form healthy red blood cells. Because it touches so many pathways, low levels can quietly show up as low mood or fatigue.

The science

Vitamin B6 is required for amino acid metabolism, serotonin and dopamine synthesis, and immune function.

Most relevant for

Mood and PMS support, plant-based eaters, and anyone on the contraceptive pill.

Key references

General wellness information, not medical advice. Consult your healthcare provider before starting any supplement. Build your personalized stack →